Dosage protocol · Hormonal & Sexual Health
HMG 0.15 mg
Typical protocol: 75 IU three times weekly for 12–16 weeks, usually combined with hCG therapy.
- Reconstitute: Add 3.0 mL bacteriostatic water → 25 IU/mL concentration.
- Typical protocol: 75 IU three times weekly for 12–16 weeks, usually combined with hCG therapy.
- Volume consideration: Each 75 IU dose = 3.0 mL, requiring a 3 mL syringe or multiple 1 mL injections.
- Storage: Lyophilized: refrigerate at 2–8 °C (35.6–46.4 °F); after reconstitution, use promptly or refrigerate and use within a few days.
BAC water3.0mL
Reconstitution
HMG dosage chart
HMG dosage chart
| Week | Dose | Draw |
|---|---|---|
| Weeks 1–12 | 75 IU0.15 mg | 3.0 mL3.0 mL |
| Weeks 13–16 (optional extension) | 75 IU0.15 mg | 3.0 mL3.0 mL |
How much to draw
The Draw column shows exactly where to stop on a U-100 insulin syringe. Different vial size or dose? The calculator below recomputes it live.
Supplies needed
Supplies needed
Peptide vial
The lyophilized compound
Bacteriostatic water
For reconstitution
U-100 insulin syringes
One per injection
Alcohol swabs
Stopper + site each time
How it works
HMG stands for human menopausal gonadotropin, generically classified as menotropins. Despite being searched for as an "HMG peptide," it is not a short synthetic peptide at all — it is a biologic hormone medication containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity, the same gonadotropins the pituitary gland normally produces.
Traditional HMG preparations are purified from the urine of postmenopausal women, whose gonadotropin levels rise once ovarian estrogen feedback declines. In the United States, an FDA-approved menotropins product is marketed as MENOPUR.[1] Potency and labeling vary by brand and country, so an informal online reference to "HMG" should not be assumed equivalent to any specific approved medicine.
Benefits & side effects
The strongest evidence for HMG sits in reproductive medicine: ovarian stimulation protocols in IVF and other assisted reproductive technology (ART) cycles, and ovulation induction in select anovulatory conditions such as polycystic ovary syndrome unresponsive to first-line treatment. Systematic reviews have compared urinary gonadotropins like HMG against recombinant FSH in ART as a treatment-category comparison, not as a declaration that one is superior for all patients.
In men, gonadotropin therapy combining hCG with an FSH-containing product such as HMG has a defined, evidence-supported role in hypogonadotropic hypogonadism, where the pituitary fails to adequately signal the testes. Evidence for broader "idiopathic" male infertility is weaker, and no credible clinical evidence supports HMG for weight loss, anti-aging, or general wellness — none of which appear anywhere in its approved labeling.
Calculator
Plan your own dose
Reconstituting a different vial size or targeting a different dose? Run the numbers.
1
Reconstitution
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mL
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Per 10 units (0.1 mL)—
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Your dose
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